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For instance, in a randomized, placebo-controlled trial in healthy adults, subcutaneous CJC-1295 injections produced sustained, dose-dependent increases in GH (two to 10 times) and IGF-1 (1.5 to three times) levels over several days, demonstrating prolonged GH axis stimulation without serious adverse effects, a hormonal milieu associated with anabolic and metabolic effects

One unit of GR activity corresponds to the amount of enzyme that catalyzes the transformation of 1 nmol of oxidized glutathione (GSSG) into its reduced form (GSH) during 1 min at 37 C per mg of protein (mU/mg)